Ecuador 1-1 Colombia
With an additional automatic qualifying spot on offer to South America for the 2026 World Cup, these two nations will both expect to comfortably qualify after making positive starts to the campaign.
As such, neither manager or set of players would likely be too disappointed with a draw, and that is the result we are predicting between two evenly matched sides.
Uruguay 1-2 Brazil
This has all of the makings of a fascinating match, especially as both sides will be looking to return to winning ways. Uruguay are certainly capable of claiming a positive result on Tuesday, but we just have a feeling that Brazil will be able to navigate their way to an important three points here.
Peru 0-2 Argentina
Peru are capable of making this an uncomfortable game for Argentina, but it is very difficult to imagine anything other than an away win on Tuesday. Argentina have so much quality throughout their side and should have too much for their opponents in this contest.
Gremio 2-1 Athletico Paranaense
While Gremio boast the third-best home record in Serie A – winning 10 games from 13 so far – Athletico have just three away wins to their name in this year’s Brasileiro. Therefore, the hosts can get back to winning ways after their derby defeat.
